About Angiosarcoma Angiosarcoma is an aggressive form of soft tissue sarcoma (STS) of endothelial cell origin that is associated with poor prognosis. Angiosarcoma has a 5-year survival rate of less than 12%, which highlights the aggressive nature of this tumor when compared to a 5-year survival rate of approximately 56% for all STS. Angiosarcoma can arise in any soft tissue structure. About half of patients present with a primary cutaneous lesion. Risk factors include prior radiation exposure as well as inflammatory damage in chronically sun exposed skin. Angiosarcoma has also been associated with chronic lymphedema. Although resection with curative intent followed by adjuvant radiotherapy is the treatment of choice for localized disease amenable to surgery, approximately 50% of these patients will develop metastases and die from the disease. basicsFurthermore, metastases are frequently present at diagnosis, and resection of metastases is rarely feasible. Read More Angiosarcoma is an extremely rare disease and meets the definition for an orphan disease in the US and European Union (EU), the two regions for which the Phase 3 TAPPAS study is planned. TRC105 has received orphan designation for the treatment of soft tissue sarcoma in both the US and EU. The annual incidence of angiosarcoma in the US was reported by the NCI in 2015 to be 475 cases.

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1), after the team’s 27-10 loss to the Cincinnati Bengals. Going into the game, he said he was “89 percent sure” it was his final game and confirmed his decision after the game, in an emotional TV interview. medical interview rating scale“That’s it,” Smith said, as he bowed his head. Steve Smith Sr. tells CBS “that’s it” after Ravens final game of the season. pic.twitter.com/EeCg8iHY9j NFLonCBS (@NFLonCBS) January 1, 2017 “This morning my wife sent me a text, and they werent here. My family wasnt here because if they were here, I would have lost it,” he said later, while speaking with media. “I enjoyed it, but you know its over, its done,” Smith continued. “I know its my time. Some people say, ‘Can I play another year?’ I probably could, but what I lose, Im not willing to risk.” When asked how it feels, going interview retirement, he replied: “A little bit of relief.

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