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“Obviously I was first to go and I thought in my mind right here to go as fast as I could but be safe… I tried to put a bit of pressure on everyone else. Luck was on my side,” said Skelton. Sweden’s Peder Fredricson took second as the only other rider in the jumpoff to score no penalties but he was nearly a second slower than Skelton’s pace. Canada’s Eric Lamaze took bronze. The 2008 gold medalist and final rider to go, Lamaze jumped a quick round on the mare Fine Lady but knocked over a rail. “I knew what I had to do… Nick was very quick and forced all the riders to go at top speed. I knew there was still a spot for a medal with four faults,” he said.
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Daratumumab bound to RBCs masks detection of antibodies to minor antigens in the patient’s serum. The determination of a patient’s ABO and Rh blood type are not impacted. Notify blood transfusion centers of this interference with serological testing and inform blood banks that a patient has received DARZALEX. Type and screen patients prior to starting DARZALEX. Interference with Determination of Complete Response – Daratumumab is a human IgG kappa monoclonal antibody that can be detected on both, the serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for the clinical monitoring of endogenous M-protein. This interference can impact the determination of complete response and of disease progression in some patients with IgG kappa myeloma protein. Adverse Reactions – The most frequently reported adverse reactions (incidence 20%) were: infusion reactions (48%), fatigue (39%), nausea (27%), back pain (23%), pyrexia (21%), cough (21%), and upper respiratory tract infection (20%). Serious adverse reactions were reported in 51 (33%) patients. The most frequent serious adverse reactions were pneumonia (6%), general physical health deterioration (3%), and pyrexia (3%). DRUG INTERACTIONS – No drug interaction studies have been performed About the Janssen Pharmaceutical Companies At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most image source promising science.
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